I did this a few weeks ago on my '13 Sequoia, but I did not flush it. Just drained the rad and the valves on the block. Replaced with Toyota red and distilled water at 50/50. The fluid I drained was as clear as the fluid I replaced, so I felt flushing was not necessary.
Pros: clear fluid after drain
Cons: no flushing needed
Vehicle:
Toyota Sequoia
